helicase-like RNA polymerase protection protein [AMR Gene Family]

Accession ARO:3007207
DefinitionHelicase-like proteins that confer resistance to antibiotics such as rifamycins by preventing or disrupting their binding to RNA polymerase.
Drug Classrifamycin antibiotic
Resistance Mechanismantibiotic target protection
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ rifampin-resistant RNA polymerase-binding protein
+ confers_resistance_to_drug_class rifamycin antibiotic [Drug Class]
1 ontology terms | Show
+ HelR

Surette MD, et al. 2022. Mol Cell : HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics. (PMID 35907401)