D-captopril [Adjuvant]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007301
DefinitionD-captopril is an isomer of L-captopril and is able to chelate certain metallo-beta-lactamases.
SMILESC[C@H](CS)C(=O)N1CCC[C@@H]1C(=O)O
PubChem447055
ChEMBLCHEMBL434965
Classification5 ontology terms | Show
Parent Term(s)5 ontology terms | Show
+ is_small_molecule_inhibitor_of NDM-1
+ is_small_molecule_inhibitor_of IMP-7
+ is_small_molecule_inhibitor_of VIM-1
+ is_small_molecule_inhibitor_of BcII
+ unclassified metallo-beta-lactamase inhibitor
Publications

Brem J, et al. 2016. Antimicrob Agents Chemother 60(1):142-50 Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers. (PMID 26482303)

Curator Acknowledgements
Curator Description Most Recent Edit