Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:3007414 |
Definition | A family of aminoglycoside 3''-O-phosphotransferase enzymes which inactivate streptomycin by catalyzing the ATP-dependent phosphorylation of the 3''-hydroxyl group, thereby conferring resistance. |
AMR Gene Family | APH(3'') |
Drug Class | aminoglycoside antibiotic |
Resistance Mechanism | antibiotic inactivation |
Classification | 10 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + antibiotic inactivation enzyme + aminoglycoside modifying enzyme + phosphorylation of antibiotic conferring resistance + antibiotic molecule + aminoglycoside phosphotransferase (APH) + aminoglycoside antibiotic [Drug Class] |
Parent Term(s) | 1 ontology terms | Show + APH(3'') [AMR Gene Family] |
Sub-Term(s) | 3 ontology terms | Show |
Curator | Description | Most Recent Edit |
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