ketoconazole [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007517
DefinitionKetoconazole is a type of imidazole antibiotic, particularly antifungal. It was one of the first available oral broad-spectrum antifungals for the treatment of systemic and superficial mycoses.
SMILESCC(=O)N1CCN(c2ccc(OCC3COC(Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1
PubChem456201
ChEBI47519
CAS65277-42-1
ChEMBLCHEMBL157101
Drug Classimidazole antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ imidazole antibiotic [Drug Class]
Sub-Term(s)
1 ontology terms | Show
Publications

Levine HB, et al. 1978. Am Rev Respir Dis 118(4):715-21 Oral therapy for experimental coccidioidomycosis with R41 400 (ketoconazole), a new imidazole. (PMID 707893)

Heel RC, et al. 1982. Drugs 23(1-2):1-36 Ketoconazole: a review of its therapeutic efficacy in superficial and systemic fungal infections. (PMID 6276122)

Curator Acknowledgements
Curator Description Most Recent Edit