imidazole antibiotic [Drug Class]

Accession ARO:3007500
DefinitionImidazoles are a group of antibiotics, particularly antifungals, derived from azoles. Imidazoles include imidazole derivatives clotrimazole, ketoconazole, miconazole, econazole and oxiconazole.
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
8 ontology terms | Show
+ clotrimazole [Antibiotic]
+ ketoconazole [Antibiotic]
+ miconazole [Antibiotic]
+ econazole [Antibiotic]
+ oxiconazole [Antibiotic]
+ Zn2Cys6 transcription factors [AMR Gene Family] confers_resistance_to_drug_class
+ Candida spp. pleiotropic drug resistance factor 1 confers_resistance_to_drug_class
+ imidazole-resistant fungal cytochrome P450 enzyme [AMR Gene Family] confers_resistance_to_drug_class

Borgers M, et al. 1980. Rev Infect Dis 2(4):520-34 Mechanism of action of antifungal drugs, with special reference to the imidazole derivatives. (PMID 7003674)

Zonios DI, et al. 2008. Semin Respir Crit Care Med 29(2):198-210 Update on azole antifungals. (PMID 18366001)