The Comprehensive Antibiotic Resistance Database

A bioinformatic database of resistance genes, their products and associated phenotypes.

4008 Ontology Terms, 2498 Reference Sequences, 1211 SNPs, 2437 Publications, 2545 AMR Detection Models

Resistome predictions: 76 pathogens, 4194 chromosomes, 4666 plasmids, 66095 WGS assemblies, 132747 alleles

Browse

The CARD is a rigorously curated collection of characterized, peer-reviewed resistance determinants and associated antibiotics, organized by the Antibiotic Resistance Ontology (ARO) and AMR gene detection models.

Analyze

The CARD includes tools for analysis of molecular sequences, including BLAST and the Resistance Gene Identifier (RGI) software for prediction of resistome based on homology and SNP models.

Download

CARD data can be downloaded in a number of formats. RGI software is available as a command-line tool. View changes in CARD curation. CARD is updated monthly.

Prevalence

A computer-generated data set on the prevalence of AMR genes and variants among the sequenced genomes, plasmids, and whole-genome shotgun assemblies available at NCBI for 76 important pathogens.

Resistomes & Variants

Computer-generated resistome predictions for the sequenced genomes, plasmids, and whole-genome shotgun assemblies available at NCBI for 76 important pathogens. Includes sequence variants beyond those reported in the scientific literature, as predicted by the Resistance Gene Identifier.