The Comprehensive Antibiotic Resistance Database

A bioinformatic database of resistance genes, their products and associated phenotypes.

3907 Ontology Terms, 2492 Reference Sequences, 1207 SNPs, 2409 Publications, 2524 AMR Detection Models

Resistome predictions: 1358 chromosome, 1622 plasmid, 34883 WGS assemblies


The CARD is a rigorously curated collection of characterized, peer-reviewed resistance determinants and associated antibiotics, organized by the Antibiotic Resistance Ontology (ARO) and AMR gene detection models.


The CARD includes tools for analysis of molecular sequences, including BLAST and the Resistance Gene Identifier (RGI) software for prediction of resistome based on homology and SNP models.


CARD data can be downloaded in a number of formats. RGI software is available as a command-line tool. View changes in CARD curation. CARD is updated monthly.


A computer-generated data set on the prevalence of AMR genes and variants among the sequenced genomes, plasmids, and whole-genome shotgun assemblies available at NCBI for clinically important pathogens.

Resistomes & Variants

Computer-generated resistome predictions for priority pathogen genomes, plasmids, and whole-genome shotgun assemblies available at NCBI. Includes sequence variants beyond those reported in the scientific literature, as predicted by the Resistance Gene Identifier.