The Comprehensive Antibiotic Resistance Database

A bioinformatic database of resistance genes, their products and associated phenotypes.

3821 Ontology Terms, 2388 Reference Sequences, 1046 SNPs, 2394 Publications, 2420 AMR Detection Models


The CARD is a rigorously curated collection of known resistance determinants and associated antibiotics, organized by the Antibiotic Resistance Ontology (ARO) and AMR gene detection models.


The CARD includes tools for analysis of molecular sequences, including BLAST and the Resistance Gene Identifier (RGI) software for prediction of resistome based on homology and SNP models.


CARD data can be downloaded in a number of formats. RGI software is available as a command-line tool. View changes in CARD curation. CARD is updated monthly.


A new computer-generated data set on the prevalence of AMR genes and variants among the sequenced genomes, plasmids, and whole-genome shotgun assemblies available at NCBI for clinically important pathogens.