antibiotic resistant DNA topoisomerase subunit parE

Accession ARO:3000115
DefinitionParE is a subunit of topoisomerase IV, which decatenates and relaxes DNA to allow access to genes for transcription or translation. Mutations in ParE prevents antibiotics from inhibiting DNA synthesis, thus conferring resistance.
Resistance Mechanismantibiotic target alteration
Classification6 ontology terms | Show
Parent Term(s)2 ontology terms | Show
2 ontology terms | Show
+ aminocoumarin resistant parE [AMR Gene Family]
+ fluoroquinolone resistant parE [AMR Gene Family]