aminoglycoside acetyltransferase (AAC)

Accession ARO:3000121
Synonym(s)aminoglycoside N-acetyltransferase
DefinitionAminoglycoside acetyltransferase enzymes modify aminoglycoside antibiotics by catalyzing the transfer of an acetyl group to one of the amino groups present in aminoglycosides, using acetyl coenzyme A as a donor substrate.
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification6 ontology terms | Show
Parent Term(s)3 ontology terms | Show
Sub-Term(s)
6 ontology terms | Show
+ AAC(3) [AMR Gene Family]
+ AAC(2') [AMR Gene Family]
+ AAC(6') [AMR Gene Family]
+ cpa acetyltransferase [AMR Gene Family]
+ amp acetyltransferase [AMR Gene Family]
+ AAC(1) [AMR Gene Family]
Publications

Ramirez MS and Tolmasky ME. 2010. Drug Resist Updat 13(6): 151-171. Aminoglycoside modifying enzymes. (PMID 20833577)