AAC(6') [AMR Gene Family]

Accession ARO:3000345
DefinitionA category of aminoglycoside N-acetyltransferase enzymes with modification regiospecificity based at the 6'-amino group of the respective antibiotic. These enzymes inactivate aminoglycoside antibiotics through acetylation of the 6-amino group of the compound.
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification8 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ aminoglycoside acetyltransferase (AAC)
+ confers_resistance_to_drug_class aminoglycoside antibiotic [Drug Class]
14 ontology terms | Show

Poole K, et al. 2005. Antimicrob. Agents Chemother. 49(2):479-87 Aminoglycoside resistance in Pseudomonas aeruginosa. (PMID 15673721)