Accession ARO:3007395
DefinitionA family of aminoglycoside 6'-N-acetyltransferase enzymes which inactivate amikacin and tobramycin through enzymatic acetylation, thereby conferring resistance to these compounds.
AMR Gene FamilyAAC(6')
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ AAC(6') [AMR Gene Family]
44 ontology terms | Show

Shaw KJ, et al. 1993. Microbiol Rev 57(1): 138-163. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. (PMID 8385262)