gramicidin A [Antibiotic]

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Accession ARO:3000222
DefinitionGramicidin A is the most abundant (more than 80%) of the three gramicidins in gramicidin D, with a tryptophan in position 11. Gramicidins form dimers in the bacterial membrane that increase the permeability of cations.
Drug Classpeptide antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ gramicidin [Antibiotic]
2 ontology terms | Show
+ cell membrane component targeted by antibiotic targeted_by_antibiotic
+ gramicidin D [Antibiotic] has_part

Kelkar DA and Chattopadhyay A. 2007. Biochim Biophys Acta 1768(9): 2011-2025. The gramicidin ion channel: a model membrane protein. (PMID 17572379)