gramicidin B [Antibiotic]

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Accession ARO:3000223
DefinitionGramicidin B is one of the three gramicidins in gramicidin D, with a phenylalanine in position 11. It is structurally similar to gramicidin A, but its ability to induce the assembly of bilayers is reduced. Gramicidins form dimers in the bacterial membrane that increase the permeability of cations.
Drug Classpeptide antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ gramicidin [Antibiotic]
2 ontology terms | Show
+ cell membrane component targeted by antibiotic targeted_by_antibiotic
+ gramicidin D [Antibiotic] has_part

Kelkar DA and Chattopadhyay A. 2007. Biochim Biophys Acta 1768(9): 2011-2025. The gramicidin ion channel: a model membrane protein. (PMID 17572379)