| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000466 |
| Synonym(s) | Zeven |
| Definition | Dalbavancin is a semisynthetic second-generation lipoglycopeptide derived from teicoplanin. It binds to the D-Ala-D-Ala terminus of peptidoglycan precursors. It is used to treat Gram-positive bacteria and can be used to treat methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. |
| SMILES | CN[C@H]1C(=O)N[C@@H]2Cc3ccc(cc3)Oc3cc4cc(c3O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3NC(=O)CCCCCCCCC(C)C)Oc3ccc(cc3Cl)[C@@H](O)[C@@H]3NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@@H](NC2=O)c2cc(cc(O)c2Cl)Oc2cc1ccc2O)c1ccc(O)c(c1)-c1c(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)cc(O)cc1[C@@H](C(=O)NCCCN(C)C)NC3=O |
| PubChem | 23724878 |
| ChEMBL | CHEMBL3301669 |
| ChEBI | 82721 |
| CAS | 171500-79-1 |
| Drug Class | glycopeptide antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + glycopeptide antibiotic [Drug Class] |
| Sub-Term(s) | 1 ontology terms | Show + acyl-D-alanyl-D-alanine targeted_by_antibiotic |
| Publications | Kim A, et al. 2007. Expert Opin Investig Drugs 16(5): 717-733. Review of dalbavancin, a novel semisynthetic lipoglycopeptide. (PMID 17461743) Guay DR. 2004. Expert Rev Anti Infect Ther 2(6): 845-852. Dalbavancin: an investigational glycopeptide. (PMID 15566329) Tatarkiewicz J, et al. 2016. Arch Med Sci 12(6):1327-1336 New agents approved for treatment of acute staphylococcal skin infections. (PMID 27904526) |
| Curator | Description | Most Recent Edit |
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