telavancin [Antibiotic]

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Accession ARO:3000488
DefinitionTelavancin is a semi-synthetic derivative of vancomycin and is a second-generation lipoglycopeptide antibiotic. Telavancin inhibits cell wall synthesis by forming a complex with the D-Ala-D-Ala terminus of peptidoglycan precursors and preventing transglycosylation.
Drug Classglycopeptide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show
+ acyl-D-alanyl-D-alanine targeted_by_antibiotic

Smith WJ and Drew RH. 2009. Drugs Today (Barc) 45(3): 159-173. Telavancin: a new lipoglycopeptide for gram-positive infections. (PMID 19436839)

Charneski L, et al. 2009. Ann Pharmacother 43(5): 928-938. Telavancin: a novel lipoglycopeptide antibiotic. (PMID 19401479)

Nannini EC and Stryjewski ME. 2008. Expert Opin Pharmacother 9(12): 2197-2207. A new lipoglycopeptide: telavancin. (PMID 18671473)