Accession ARO:3000695
DefinitionActinomycins are peptide antibiotics that interact with DNA. This prevents RNA synthesis, thus preventing the production of proteins vital to the cell.
Drug Classpeptide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ peptide antibiotic [Drug Class]
2 ontology terms | Show
+ Dactinomycin [Antibiotic]
+ transcription complex DNA targeted_by

Sobell HM. 1985. Proc Natl Acad Sci U S A 82(16): 5328-5331. Actinomycin and DNA transcription. (PMID 2410919)