| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000741 |
| Definition | DNA in the transcriptional complex is partially unwound, allowing antibiotics to target exposed bases and prevent DNA transcription. |
| Drug Class | peptide antibiotic, nonribosomal peptide antibiotics, glycopeptide antibiotic, nitrofuran antibiotic |
| Classification | 15 ontology terms | Show + process or component of antibiotic biology or chemistry + antibiotic molecule + peptide antibiotic [Drug Class] + nonribosomal peptide antibiotics [Drug Class] + antibiotic mixture + glycopeptide antibiotic [Drug Class] + nitrofuran antibiotic [Drug Class] + antibiotic target + bleomycin [Antibiotic] + nucleic acid targeted by antibiotic + actinomycin + bleomycin B2 [Antibiotic] + bleomycin A2 [Antibiotic] + bleomycinic acid [Antibiotic] + nitrofurantoin [Antibiotic] |
| Parent Term(s) | 3 ontology terms | Show |
| Publications | Sobell HM. 1985. Proc Natl Acad Sci U S A 82(16): 5328-5331. Actinomycin and DNA transcription. (PMID 2410919) GOLDBERG IH, et al. 1962. Proc Natl Acad Sci U S A 48: 2094-2101. Basis of actinomycin action. I. DNA binding and inhibition of RNA-polymerase synthetic reactions by actinomycin. (PMID 13948669) |
| Curator | Description | Most Recent Edit |
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