50S ribosomal subunit

Accession ARO:3000727
DefinitionThe larger of two ribosomal subunits that make up the 70S bacterial ribosome.
Drug Classmacrolide antibiotic
Classification2 ontology terms | Show
Parent Term(s)2 ontology terms | Show
2 ontology terms | Show

Kirillov SV, et al. 1999. RNA 5(8): 1003-1013. Peptidyl transferase antibiotics perturb the relative positioning of the 3'-terminal adenosine of P/P'-site-bound tRNA and 23S rRNA in the ribosome. (PMID 10445875)

Polacek N and Mankin AS. 2005. Crit Rev Biochem Mol Biol 40(5): 285-311. The ribosomal peptidyl transferase center: structure, function, evolution, inhibition. (PMID 16257828)