| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000740 |
| Synonym(s) | RNA |
| Definition | Many types of ribonucleic acids (RNAs) are targeted by antibiotics, including mRNA templates and ribosomal RNA. Some antibiotics target all RNAs and cause strand breaks. |
| Drug Class | glycopeptide antibiotic |
| Classification | 6 ontology terms | Show + process or component of antibiotic biology or chemistry + antibiotic molecule + antibiotic mixture + glycopeptide antibiotic [Drug Class] + antibiotic target + bleomycin [Antibiotic] |
| Parent Term(s) | 5 ontology terms | Show + targeted_by_antibiotic bleomycin [Antibiotic] + targeted_by_antibiotic bleomycinic acid [Antibiotic] + targeted_by_antibiotic bleomycin A2 [Antibiotic] + targeted_by_antibiotic bleomycin B2 [Antibiotic] + nucleic acid targeted by antibiotic |
| Sub-Term(s) | 4 ontology terms | Show |
| Publications | Wank H, et al. 1994. J Mol Biol 236(4): 1001-1010. Peptide antibiotics of the tuberactinomycin family as inhibitors of group I intron RNA splicing. (PMID 7509881) Muller WE and Zahn RK. 1977. Prog Biochem Pharmacol 11: 28-47. Effect of bleomycin on DNA, RNA, protein, chromatin and on cell transformation by oncogenic RNA viruses. (PMID 63969) Carter BJ, et al. 1990. Proc Natl Acad Sci U S A 87(23): 9373-9377. Site-specific cleavage of RNA by Fe(II).bleomycin. (PMID 1701259) Chen J and Stubbe J. 2005. Nat Rev Cancer 5(2): 102-112. Bleomycins: towards better therapeutics. (PMID 15685195) |
| Curator | Description | Most Recent Edit |
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