ribonucleic acid

Accession ARO:3000740
DefinitionMany types of ribonucleic acids (RNAs) are targeted by antibiotics, including mRNA templates and ribosomal RNA. Some antibiotics target all RNAs and cause strand breaks.
Classification2 ontology terms | Show
Parent Term(s)5 ontology terms | Show
+ nucleic acid targeted by antibiotic
+ targeted_by_antibiotic bleomycin A2 [Antibiotic]
+ targeted_by_antibiotic bleomycin B2 [Antibiotic]
+ targeted_by_antibiotic bleomycinic acid [Antibiotic]
+ targeted_by_antibiotic bleomycin [Antibiotic]
4 ontology terms | Show

Wank H, et al. 1994. J Mol Biol 236(4): 1001-1010. Peptide antibiotics of the tuberactinomycin family as inhibitors of group I intron RNA splicing. (PMID 7509881)

Muller WE and Zahn RK. 1977. Prog Biochem Pharmacol 11: 28-47. Effect of bleomycin on DNA, RNA, protein, chromatin and on cell transformation by oncogenic RNA viruses. (PMID 63969)

Carter BJ, et al. 1990. Proc Natl Acad Sci U S A 87(23): 9373-9377. Site-specific cleavage of RNA by Fe(II).bleomycin. (PMID 1701259)

Chen J and Stubbe J. 2005. Nat Rev Cancer 5(2): 102-112. Bleomycins: towards better therapeutics. (PMID 15685195)