LFF571 [Antibiotic]

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Accession ARO:3003414
DefinitionLFF571 is a novel semi-synthetic thiopeptide antibiotic derived from GE2270. It has been shown to possess potent in vitro and in vivo activity against Gram-positive bacteria. It is hypothesized that it a translation inhibitor leading to cell death.
Drug Classelfamycin antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
2 ontology terms | Show

Leeds JA, et al. 2012. Antimicrob Agents Chemother 56(8): 4463-4465. Mechanism of action of and mechanism of reduced susceptibility to the novel anti-Clostridium difficile compound LFF571. (PMID 22644023)