elongation factor Tu

Accession ARO:3000731
DefinitionElongation factor Tu is required for peptide elongation in bacterial protein synthesis.
Drug Classelfamycin antibiotic
Classification2 ontology terms | Show
Parent Term(s)7 ontology terms | Show
+ protein synthesis machinery targeted by antibiotic
+ targeted_by elfamycin antibiotic [Drug Class]
+ targeted_by_antibiotic LFF571 [Antibiotic]
+ targeted_by_antibiotic GE2270A [Antibiotic]
+ targeted_by_antibiotic kirromycin-like antibiotics
+ targeted_by_antibiotic pulvomycin [Antibiotic]
+ targeted_by_antibiotic enacyloxin IIa [Antibiotic]
11 ontology terms | Show

Wolf H, et al. 1978. Proc Natl Acad Sci U S A 75(11): 5324-5328. Pulvomycin, an inhibitor of protein biosynthesis preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA. (PMID 364475)

Nyborg J and Liljas A. 1998. FEBS Lett 430(1-2): 95-99. Protein biosynthesis: structural studies of the elongation cycle. (PMID 9678602)