sitafloxacin [Antibiotic]

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Accession ARO:3003690
DefinitionSitafloxacin is a fluoroquinolone active against multi-resistant Gram-positive and negative pathogens. Sitafloxacin shows inhibitory activity against DNA gyrase and topoisomerase IV, which blocks bacterial DNA replication, thereby causing double-stranded breaks in the bacterial chromosome.
Drug Classfluoroquinolone antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
1 ontology terms | Show

Keating GM, et al. 2011. Drugs 71(6):731-44 Sitafloxacin: in bacterial infections. (PMID 21504249)