Lysocin E [Antibiotic]

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Accession ARO:3003915
DefinitionA drug which binds to menaquinone in the bacterial cell membrane. Binding of Lysocin to menaquinone facilitates lysis of the cell.
Drug Classpeptide antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
2 ontology terms | Show
+ menaquinone [Antibiotic] targeted_by_antibiotic
+ Staphylococcus aureus menA with mutation conferring resistance to lysocin confers_resistance_to_antibiotic

Hamamoto H, et al. 2015. Nat. Chem. Biol. 11(2):127-33 Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane. (PMID 25485686)