| Accession | MO:0000029 |
| Definition | The BLASTP bit-score is a numerical value that describes the overall quality of an alignment. Higher numbers correspond to higher similarity. The bit-score (S) is determined by the following formula: S = (λ × S − lnK)/ ln2 where λ is the Gumble distribution constant, S is the raw alignment score, and K is a constant associated with the scoring matrix. This parameter is used by AMR detection models that use a protein reference sequence, e.g. the protein homolog model. The BLASTP bit-score parameter is a curated value determined from BLASTP analysis of the canonical reference sequence of a specific AMR-associated protein against the database of CARD reference sequence. This value establishes a threshold for computational prediction of RGI Strict match (above bit-score cut-off) or Loose match (below bit-score cut-off). |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 8 ontology terms | Show + part_of protein homolog model + part_of protein variant model + part_of protein knockout model + part_of protein overexpression model + detection parameter + fungal protein variant model + fungal protein homolog model + part_of fungal protein knockout model |