phosphoethanolamine transferase conferring colistin resistance

Accession ARO:3004112
Synonym(s)PEtN transferase
DefinitionThis group of enzymes catalyzes the addition of a phosphoethanolamine group to another molecule. The addition of this moiety to lipid A in bacterial species is often associated with polymyxin (otherwise known as colistin) resistance.
Drug Classpeptide antibiotic
Resistance Mechanismantibiotic target alteration
Classification9 ontology terms | Show
Parent Term(s)2 ontology terms | Show
Sub-Term(s)
3 ontology terms | Show
Publications

Sun J, et al. 2017. MBio 8(3): Deciphering MCR-2 Colistin Resistance.. (PMID 28487432)

Liu YY, et al. 2015. Lancet Infect Dis : Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.. (PMID 26603172)