NmcA beta-lactamase [AMR Gene Family]

Accession ARO:3004195
DefinitionnmcA beta-lactamases are chromosomal-encoded Class A beta-lactamases first isolated from Enterobacter cloacae, specifically a clinical strain known as NOR-1. nmcA beta-lactamases have been shown to hydrolyze carbapenems.
Drug Classcarbapenem
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ class A beta-lactamase
Sub-Term(s)
1 ontology terms | Show
+ NmcA
Publications

Naas T, et al. 1994. Proc Natl Acad Sci U S A 91(16): 7693-7697. Analysis of a carbapenem-hydrolyzing class A beta-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein. (PMID 8052644)