blaZ beta-lactamase [AMR Gene Family]

Accession ARO:3004197
DefinitionblaZ beta-lactamases are Class A beta-lactamases. These beta-lactamases are responsible for penicillin resistance in Staphylococcus aureus.
Drug Classpenam
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class penam [Drug Class]
+ class A beta-lactamase
Sub-Term(s)
1 ontology terms | Show
Publications

McLaughlin JR, et al. 1981. J Biol Chem 256(21): 11283-11291. Unique features in the ribosome binding site sequence of the gram-positive Staphylococcus aureus beta-lactamase gene. (PMID 6793593)

Pence MA, et al. 2015. PLoS ONE 10(8):e0136605 Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence. (PMID 26305782)