Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:3004244 |
Definition | The DnaA family of replication initiation proteins interact with RNA polymerase to confer resistance against rifampicin anitibiotics. |
Drug Class | rifamycin antibiotic |
Resistance Mechanism | antibiotic target protection |
Classification | 6 ontology terms | Show |
Parent Term(s) | 2 ontology terms | Show + confers_resistance_to_drug_class rifamycin antibiotic [Drug Class] + rifampin-resistant RNA polymerase-binding protein |
Sub-Term(s) | 1 ontology terms | Show + DnaA |
Publications | Flatten I, et al. 2009. Mol Microbiol 71(4): 1018-1030. DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin. (PMID 19170875) Salguero I, et al. 2011. Microbiology (Reading, Engl.) 157(Pt 7):1955-67 Overlap of replication rounds disturbs the progression of replicating forks in a ribonucleotide reductase mutant of Escherichia coli. (PMID 21527473) |
Curator | Description | Most Recent Edit |
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