Rho-protein activator toxins [Virulence Factor]

Accession VIRO:0000307
DefinitionGroup of toxins which exert their toxic effect by activating rho proteins in order to enhance actin polymerization within the host cell
Classification7 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ ADP-Ribosylation [Virulence Mechanism]
+ Actin-affecting toxins [Virulence Mechanism]
3 ontology terms | Show
+ Deamidation [Virulence Mechanism] participates_in
+ Pneumolysin
+ CNFy

Aktories K, et al. 2017. Handb Exp Pharmacol 235:179-206 ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins. (PMID 27316913)