Accession VIRO:0000591
DefinitionLukA (also known as LukG) is one of the F-class component of LukAB (also known as LukGH). LukA may combine with the S component LukB produced by Staphylococcus aureus to form an active toxin molecule. LukAB is unique as bi-component leukocidin because its units assemble before it is secreted, where as such systems generally assemble when they attach to the cell.
Classification14 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ LukAB subunit
+ part_of LukAB

Badarau A, et al. 2017. Adv. Exp. Med. Biol. 966:15-35 Structure and Function of the Two-Component Cytotoxins of Staphylococcus aureus - Learnings for Designing Novel Therapeutics. (PMID 28455832)

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