SCO beta-lactamase [AMR Gene Family]

Accession ARO:3004855
DefinitionSCOs are Class A beta-lactamases that confer resistance to a narrow range of penams, with some minor activity on cephalosporins and carbapenems.
Drug Classpenam
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ class A beta-lactamase
+ confers_resistance_to_drug_class penam [Drug Class]
1 ontology terms | Show

Papagiannitsis CC, et al. 2011. Antimicrob. Agents Chemother. 55(1):376-81 Sequence of pR3521, an IncB plasmid from Escherichia coli encoding ACC-4, SCO-1, and TEM-1 beta-lactamases. (PMID 20956594)

Poirel L, et al. 2007. Antimicrob. Agents Chemother. 51(6):2179-84 Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina. (PMID 17420213)

Papagiannitsis CC, et al. 2007. Antimicrob Agents Chemother 51(6): 2185-2188. SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli. (PMID 17353248)