ME1071 [Adjuvant]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007305
DefinitionME1071 is an experimental metallo-beta-lactamase inhibitor.
SMILESCC/C(C(=O)[O-])=C(\CC)C(=O)[O-].[Na+].[Na+]
PubChem16064853
ChEMBLCHEMBL1673299
Classification5 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ is_small_molecule_inhibitor_of NDM-1
+ is_small_molecule_inhibitor_of IMP-1
+ is_small_molecule_inhibitor_of VIM-2
+ unclassified metallo-beta-lactamase inhibitor
Publications

Yamada K, et al. 2013. Int J Antimicrob Agents 42(3):238-43 In vivo efficacy of biapenem with ME1071, a novel metallo-β-lactamase (MBL) inhibitor, in a murine model mimicking ventilator-associated pneumonia caused by MBL-producing Pseudomonas aeruginosa. (PMID 23891525)

Curator Acknowledgements
Curator Description Most Recent Edit