Accession ARO:3007413
DefinitionA family of aminoglycoside 3'-O-phosphotransferase enzymes which inactivate kanamycin and neomycin by catalyzing the ATP-dependent phosphorylation of these antibiotics, thereby conferring resistance to these compounds. It is also possible to observe low-level sub-breakpoint amikacin resistance dependent on testing standards and breakpoint criteria.
AMR Gene FamilyAPH(3')
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ APH(3') [AMR Gene Family]
1 ontology terms | Show