iboxamycin [Antibiotic]

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Accession ARO:3007636
DefinitionIboxamycin is a fully synthetic lincosamide antibiotic. Like other lincosamides, it selectively targets the bacterial ribosome and prevents elongation of the peptide chain. Iboxamycin has been shown to be effective against bacterial strains otherwise resistant to licosamide antibiotics.
Drug Classlincosamide antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ lincosamide antibiotic [Drug Class]
5 ontology terms | Show
+ vmlR confers_resistance_to_antibiotic
+ Clostridioides difficile cplR confers_resistance_to_antibiotic
+ Clostridium perfringes cplR confers_resistance_to_antibiotic
+ Clostridium sporogenes cplR confers_resistance_to_antibiotic
+ Neobacillus vireti vmlR2 confers_resistance_to_antibiotic

Mitcheltree MJ, et al. 2021. Nature 599(7885):507-512 A synthetic antibiotic class overcoming bacterial multidrug resistance. (PMID 34707295)