Neobacillus vireti vmlR2

Accession ARO:3007646
DefinitionvmlR2 is an ABC-F ATPase ribosomal protection protein from Neobacillus vireti (formerly known as Bacillus vireti). This representative of the ARE2 subfamily has an unusually long linker domain. Confers resistance to some lincosamide and nucleoside antibiotics.
AMR Gene FamilyMiscellaneous ABC-F subfamily ATP-binding cassette ribosomal protection proteins
Drug Classnucleoside antibiotic, streptogramin antibiotic, pleuromutilin antibiotic, streptogramin A antibiotic, lincosamide antibiotic
Resistance Mechanismantibiotic target protection
Classification14 ontology terms | Show
Parent Term(s)7 ontology terms | Show
+ confers_resistance_to_antibiotic iboxamycin [Antibiotic]
+ confers_resistance_to_antibiotic A201A [Antibiotic]
+ confers_resistance_to_antibiotic hygromycin A [Antibiotic]
+ confers_resistance_to_antibiotic retapamulin [Antibiotic]
+ confers_resistance_to_antibiotic tiamulin [Antibiotic]
+ confers_resistance_to_antibiotic virginiamycin M1 [Antibiotic]
+ Miscellaneous ABC-F subfamily ATP-binding cassette ribosomal protection proteins [AMR Gene Family]

Obana N, et al. 2023. Nucleic Acids Res 51(9):4536-4554 Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR. (PMID 36951104)