SPM beta-lactamase [AMR Gene Family]

Accession ARO:3000580
DefinitionSao Paulo metallo-beta-lactamase (SPM-1) confers resistance to carbapenem in Pseudomonas aeruginosa
Drug Classcarbapenem
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ subclass B1 (metallo-) beta-lactamase
Sub-Term(s)
1 ontology terms | Show
Publications

Zavascki AP, et al. 2005. J. Antimicrob. Chemother. 56(6):1148-51 Outbreak of carbapenem-resistant Pseudomonas aeruginosa producing SPM-1 metallo-{beta}-lactamase in a teaching hospital in southern Brazil. (PMID 16239284)

Toleman MA, et al. 2002. J. Antimicrob. Chemother. 50(5):673-9 Molecular characterization of SPM-1, a novel metallo-beta-lactamase isolated in Latin America: report from the SENTRY antimicrobial surveillance programme. (PMID 12407123)

Gales AC, et al. 2003. J. Antimicrob. Chemother. 52(4):699-702 Dissemination in distinct Brazilian regions of an epidemic carbapenem-resistant Pseudomonas aeruginosa producing SPM metallo-beta-lactamase. (PMID 12951331)