Accession | ARO:3000869 |
Definition | AcetylCoA dependent acetyltransferase that acetylate streptothricins such as nourseothricin at position 16 (beta position of beta-lysine). |
Drug Class | nucleoside antibiotic |
Resistance Mechanism | antibiotic inactivation |
Classification | 5 ontology terms | Show |
Parent Term(s) | 3 ontology terms | Show + confers_resistance_to_drug_class nucleoside antibiotic [Drug Class] + participates_in acylation of antibiotic conferring resistance + antibiotic inactivation enzyme |
Sub-Term(s) | 5 ontology terms | Show |
Publications | Zahringer U, et al. 1993. FEMS Microbiol Lett 110(3): 331-334. Nourseothricin (streptothricin) inactivated by a plasmid pIE636 encoded acetyl transferase of Escherichia coli: location of the acetyl group. (PMID 8394835) Kobayashi T, et al. 1987. J Antibiot (Tokyo) 40(7): 1016-1022. Purification and biochemical characterization of streptothricin acetyltransferase coded by the cloned streptothricin-resistance gene of Streptomyces lavendulae. (PMID 3624064) |
Curator | Description | Most Recent Edit |
---|