BEL beta-lactamase [AMR Gene Family]

Accession ARO:3002384
DefinitionBEL beta-lactamases are class A expanded-spectrum beta-lactamases that are inhibited by clavulanic acid. They are chromosomally encoded and hydrolyze most cephalosporins and aztreonam.
Drug Classmonobactam, cephalosporin, penam
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ confers_resistance_to_drug_class monobactam [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
+ class A beta-lactamase
Sub-Term(s)
3 ontology terms | Show
Publications

Poirel L, et al. 2005. Antimicrob Agents Chemother 49(9): 3743-3748. BEL-1, a novel clavulanic acid-inhibited extended-spectrum beta-lactamase, and the class 1 integron In120 in Pseudomonas aeruginosa. (PMID 16127048)