pyrazinamide [Antibiotic]

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Accession ARO:3003413
DefinitionPyrazinamide is an antimycobacterial. It is highly specific and active only against Mycobacterium tuberculosis. This compound is a prodrug and needs to be activated inside the cell. It interferes with the bacterium's ability to synthesize new fatty acids, causing cell death.
Drug Classpyrazine antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ pyrazine antibiotic [Drug Class]
12 ontology terms | Show

Zhang Y, et al. 2014. Microbiol Spectr 2(4):MGM2-0023-2013 Mechanisms of Pyrazinamide Action and Resistance. (PMID 26104205)