Rho-protein inactivator toxins [Virulence Factor]

Accession VIRO:0000308
DefinitionGroup of toxins which exert their toxic effect by inactivating rho proteins in order to modify actin polymerization within the host cell
Classification7 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ ADP-Ribosylation [Virulence Mechanism]
+ Actin-affecting toxins [Virulence Mechanism]
4 ontology terms | Show
+ AMPylation [Virulence Mechanism] participates_in
+ Glycosylation [Virulence Mechanism] participates_in
+ Proteolytic cleavage [Virulence Mechanism] participates_in
+ exoenzyme S

Aktories K, et al. 2017. Handb Exp Pharmacol 235:179-206 ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins. (PMID 27316913)