BLI-489 [Adjuvant]

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Accession ARO:3007141
DefinitionBLI-489 is an experimental beta-lactamase inhibitor that exhibits broad spectrum activity against class A, B, and D carbapenemases.
Classification5 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ beta-lactam derived beta-lactamase inhibitor
+ is_small_molecule_inhibitor KPC-2
+ is_small_molecule_inhibitor NDM-5
+ is_small_molecule_inhibitor OXA-23

Shi S, et al. 2022. J Antimicrob Chemother 77(5):1301-1305 Synergistic effect of the novel β-lactamase inhibitor BLI-489 combined with imipenem or meropenem against diverse carbapenemase-producing carbapenem-resistant Enterobacterales. (PMID 35165715)