class A Mycobacterium abscessus beta-lactamase [AMR Gene Family]

Accession ARO:3007179
DefinitionClass A beta-lactamse from M. abscessus.
Drug Classpenam, penem, cephalosporin
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ class A beta-lactamase
+ confers_resistance_to_drug_class penam [Drug Class]
+ confers_resistance_to_drug_class penem [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
1 ontology terms | Show

Soroka D, et al. 2014. J Antimicrob Chemother 69(3):691-6 Characterization of broad-spectrum Mycobacterium abscessus class A β-lactamase. (PMID 24132992)

Lefebvre AL, et al. 2017. Antimicrob Agents Chemother 61(4): Inhibition of the β-Lactamase BlaMab by Avibactam Improves the In Vitro and In Vivo Efficacy of Imipenem against Mycobacterium abscessus. (PMID 28096155)