Accession | ARO:3007181 |
Definition | Class A beta-lactamase from M. tuberculosis. |
Drug Class | cephalosporin, penicillin beta-lactam |
Resistance Mechanism | antibiotic inactivation |
Classification | 10 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + antibiotic inactivation enzyme + hydrolysis of antibiotic conferring resistance + antibiotic molecule + hydrolysis of beta-lactam antibiotic by serine beta-lactamase + beta-lactam antibiotic + beta-lactamase |
Parent Term(s) | 3 ontology terms | Show + confers_resistance_to_drug_class cephalosporin [Drug Class] + confers_resistance_to_drug_class penicillin beta-lactam [Drug Class] + class A beta-lactamase |
Sub-Term(s) | 1 ontology terms | Show + blaC |
Publications | Tremblay LW, et al. 2010. Biochemistry 49(17):3766-73 Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem. (PMID 20353175) Soroka D, et al. 2014. J Antimicrob Chemother 69(3):691-6 Characterization of broad-spectrum Mycobacterium abscessus class A β-lactamase. (PMID 24132992) |
Curator | Description | Most Recent Edit |
---|