puromycin [Antibiotic]

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Accession ARO:0000047
Synonym(s)Puromycin dihydrochloride Puromycin hydrochloride Stylomycin dihydrochloride
DefinitionPuromycin is an aminonucleoside antibiotic, derived from Streptomyces alboniger, that causes premature chain termination during ribosomal protein translation.
Drug Classnucleoside antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
5 ontology terms | Show
+ 30S ribosomal subunit P-site targeted_by_antibiotic
+ bmr confers_resistance_to_antibiotic
+ mdtM confers_resistance_to_antibiotic
+ MdtNOP confers_resistance_to_antibiotic
+ lmrAB Operon confers_resistance_to_antibiotic

Ahmed M, et al. 1995. J Bacteriol 177(14): 3904-3910. Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated. (PMID 7608059)