Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:0000047 |
Synonym(s) | Puromycin dihydrochloride Puromycin hydrochloride Stylomycin dihydrochloride |
Definition | Puromycin is an aminonucleoside antibiotic, derived from Streptomyces alboniger, that causes premature chain termination during ribosomal protein translation. |
SMILES | COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)[C@H](n3cnc4c(N(C)C)ncnc43)O[C@@H]2CO)cc1 |
PubChem | 439530 |
ChEMBL | CHEMBL469912 |
ChEBI | 17939 |
CAS | 53-79-2 |
Drug Class | nucleoside antibiotic |
Classification | 3 ontology terms | Show |
Parent Term(s) | 1 ontology terms | Show |
Sub-Term(s) | 5 ontology terms | Show + 30S ribosomal subunit P-site targeted_by_antibiotic + bmr confers_resistance_to_antibiotic + mdtM confers_resistance_to_antibiotic + MdtNOP confers_resistance_to_antibiotic + lmrAB Operon confers_resistance_to_antibiotic |
Publications | Ahmed M, et al. 1995. J Bacteriol 177(14): 3904-3910. Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated. (PMID 7608059) |
Curator | Description | Most Recent Edit |
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