VEB beta-lactamase [AMR Gene Family]

Accession ARO:3000043
DefinitionVEB beta-lactamases or Vietnamese extended-spectrum beta-lactamases are class A beta-lactamases that confer high-level resistance to oxyimino cephalosporins and to aztreonam.
Drug Classcephalosporin, monobactam
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ class A beta-lactamase
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class monobactam [Drug Class]
25 ontology terms | Show

Poirel L, et al. 1999. Antimicrob Agents Chemother 43(3): 573-581. Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum beta-lactamase encoded by an Escherichia coli integron gene. (PMID 10049269)