FOX beta-lactamase [AMR Gene Family]

Accession ARO:3000067
DefinitionFOX beta-lactamases are plasmid-encoded AmpC-type beta-lactamase which conferred resistance to broad-spectrum cephalosporins and cephamycins.
Drug Classcephalosporin, cephamycin
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ class C beta-lactamase
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class cephamycin [Drug Class]
16 ontology terms | Show

Gonzalez Leiza M, et al. 1994. Antimicrob Agents Chemother 38(9): 2150-2157. Gene sequence and biochemical characterization of FOX-1 from Klebsiella pneumoniae, a new AmpC-type plasmid-mediated beta-lactamase with two molecular variants. (PMID 7811034)