Bc beta-lactamase [AMR Gene Family]

Accession ARO:3000577
DefinitionBacillus cereus beta-lactamases are zinc metallo-beta-lactamases that hydrolyze a large number of penicillins and cephalosporins.
Drug Classcephalosporin, penam
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
+ subclass B1 (metallo-) beta-lactamase
2 ontology terms | Show
+ BcI
+ BcII

Carfi A, et al. 1995. EMBO J 14(20): 4914-4921. The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. (PMID 7588620)