fluoroquinolone resistant gyrB [AMR Gene Family]

Accession ARO:3000864
DefinitionPoint mutations in DNA gyrase subunit B (gyrB) observed in Mycobacterium tuberculosis can result in resistance to fluoroquinolones.
Drug Classfluoroquinolone antibiotic
Resistance Mechanismantibiotic target alteration
Classification10 ontology terms | Show
Parent Term(s)4 ontology terms | Show
Sub-Term(s)
6 ontology terms | Show
Publications

Maruri F, et al. 2012. J Antimicrob Chemother 67(4): 819-831. A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system. (PMID 22279180)