Accession | ARO:3000913 |
Synonym(s) | IRT2-2 IT-13 |
Definition | TEM-44 is an inhibitor-resistant beta-lactamase that has been found in clinical isolates. |
AMR Gene Family | TEM beta-lactamase |
Drug Class | penam, monobactam, cephalosporin, penem |
Resistance Mechanism | antibiotic inactivation |
Classification | 17 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + antibiotic molecule + determinant of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + beta-lactam antibiotic + antibiotic inactivation enzyme + hydrolysis of antibiotic conferring resistance + cephem + hydrolysis of beta-lactam antibiotic by serine beta-lactamase + penam [Drug Class] + beta-lactamase + ampicillin [Antibiotic] + monobactam [Drug Class] + class A beta-lactamase + cephalosporin [Drug Class] + penem [Drug Class] |
Parent Term(s) | 1 ontology terms | Show + TEM beta-lactamase [AMR Gene Family] |
Publications | Bret L, et al. 1996. J Antimicrob Chemother 38(2): 183-191. Characterization of an inhibitor-resistant enzyme IRT-2 derived from TEM-2 beta-lactamase produced by Proteus mirabilis strains. (PMID 8877532) |