ampicillin [Antibiotic]

Download Sequences


Accession ARO:3000637
Synonym(s)ampicillin acid AMP Principen
DefinitionAmpicillin is a penicillin derivative that is highly acid stable, with its activity similar to benzylpenicillin.
Drug Classpenam
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ penam [Drug Class]
Sub-Term(s)
15 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ ampicillin-sulbactam has_part
+ MexAB-OprM confers_resistance_to_antibiotic
+ MexAB-OprM with MexR mutations confers resistance to multiple antibiotics confers_resistance_to_antibiotic
+ TEM-1 confers_resistance_to_antibiotic
+ SHV-1 confers_resistance_to_antibiotic
+ OXA-2 confers_resistance_to_antibiotic
+ NmcA confers_resistance_to_antibiotic
+ AcrAB-TolC confers_resistance_to_antibiotic
+ Escherichia coli AcrAB-TolC with AcrR mutation conferring resistance to ciprofloxacin, tetracycline, and ceftazidime confers_resistance_to_antibiotic
+ Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline confers_resistance_to_antibiotic
+ OXA-50 confers_resistance_to_antibiotic
+ MexAB-OprM with CpxR regulator conferring resistance to ciprofloxacin, ceftazidime, and aztreonam confers_resistance_to_antibiotic
+ MexAB-OprM with NalD mutations conferring resistance to multiple antibiotics confers_resistance_to_antibiotic
+ MexAB-OprM with NalC mutations conferring resistance to aztreonam confers_resistance_to_antibiotic
Publications

Fabbri A, et al. 1988. Chemioterapia 7(5): 306-308. In vitro activity of sulbactam/ampicillin and ampicillin against methicillin-sensitive and methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis. (PMID 3224398)

Liss RH, et al. 1980. Scand J Infect Dis Suppl 20: 1-14. Comparative study of erythromycin, amoxicillin and ampicillin antimicrobial activity against human respiratory tract pathogens. (PMID 44765)