ampicillin [Antibiotic]

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Accession ARO:3000637
Synonym(s)AMP ampicillin acid Principen
DefinitionAmpicillin is a penicillin derivative that is highly acid stable, with its activity similar to benzylpenicillin.
Drug Classpenam
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ penam [Drug Class]
42 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ ampicillin-sulbactam [Antibiotic+Adjuvant] has_part
+ MexAB-OprM confers_resistance_to_antibiotic
+ MexAB-OprM with MexR mutations confers resistance to multiple antibiotics confers_resistance_to_antibiotic
+ TEM-1 confers_resistance_to_antibiotic
+ SHV-1 confers_resistance_to_antibiotic
+ OXA-2 confers_resistance_to_antibiotic
+ NmcA confers_resistance_to_antibiotic
+ AcrAB-TolC confers_resistance_to_antibiotic
+ OXA-50 confers_resistance_to_antibiotic
+ MexAB-OprM with CpxR regulator conferring resistance to ciprofloxacin, ceftazidime, and aztreonam confers_resistance_to_antibiotic
+ MexAB-OprM with NalD mutations conferring resistance to multiple antibiotics confers_resistance_to_antibiotic
+ MexAB-OprM with NalC mutations conferring resistance to aztreonam confers_resistance_to_antibiotic
+ TEM beta-lactamase [AMR Gene Family] confers_resistance_to_antibiotic
+ blaS1 confers_resistance_to_antibiotic
+ CMY-2 confers_resistance_to_antibiotic
+ CTX-M-3 confers_resistance_to_antibiotic
+ CTX-M-27 confers_resistance_to_antibiotic
+ OXA-1 confers_resistance_to_antibiotic
+ TEM-30 confers_resistance_to_antibiotic
+ CTX-M-15 confers_resistance_to_antibiotic
+ PDC-3 confers_resistance_to_antibiotic
+ PDC-5 confers_resistance_to_antibiotic
+ mdeA confers_resistance_to_antibiotic
+ VAM-1 confers_resistance_to_antibiotic
+ Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics confers_resistance_to_antibiotic
+ PRC-1 confers_resistance_to_antibiotic
+ Klebsiella pneumoniae OmpK35 confers_resistance_to_antibiotic
+ VIM-63 confers_resistance_to_antibiotic
+ KBL-1 confers_resistance_to_antibiotic
+ VMB-1 confers_resistance_to_antibiotic
+ VHW-1 confers_resistance_to_antibiotic
+ VHH-1 confers_resistance_to_antibiotic
+ PJM-1 confers_resistance_to_antibiotic
+ SSA confers_resistance_to_antibiotic
+ LAQ-1 confers_resistance_to_antibiotic
+ WUS-1 confers_resistance_to_antibiotic
+ EBR-5 confers_resistance_to_antibiotic
+ Streptococcus pyogenes PBP2x conferring resistance to beta-lactam antibiotics confers_resistance_to_antibiotic
+ CAE-1 confers_resistance_to_antibiotic
+ PSZ-1 confers_resistance_to_antibiotic
+ AMZ-1 confers_resistance_to_antibiotic

Fabbri A, et al. 1988. Chemioterapia 7(5): 306-308. In vitro activity of sulbactam/ampicillin and ampicillin against methicillin-sensitive and methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis. (PMID 3224398)

Liss RH, et al. 1980. Scand J Infect Dis Suppl 20: 1-14. Comparative study of erythromycin, amoxicillin and ampicillin antimicrobial activity against human respiratory tract pathogens. (PMID 44765)