Accession | ARO:3000932 |
Synonym(s) | IRT-16 |
Definition | TEM-65 is an inhibitor-resistant beta-lactamase that has been found in clinical isolates. |
AMR Gene Family | TEM beta-lactamase |
Drug Class | penam, cephalosporin, penem, monobactam |
Resistance Mechanism | antibiotic inactivation |
Classification | 17 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + determinant of antibiotic resistance + antibiotic molecule + beta-lactam antibiotic + hydrolysis of antibiotic conferring resistance + antibiotic inactivation enzyme + beta-lactamase + cephem + hydrolysis of beta-lactam antibiotic by serine beta-lactamase + penam [Drug Class] + cephalosporin [Drug Class] + penem [Drug Class] + class A beta-lactamase + ampicillin [Antibiotic] + monobactam [Drug Class] |
Parent Term(s) | 1 ontology terms | Show + TEM beta-lactamase [AMR Gene Family] |
Publications | Bonnet R, et al. 1999. Antimicrob Agents Chemother 43(11): 2671-2677. Diversity of TEM mutants in Proteus mirabilis. (PMID 10543745) |